Tissue-resident memory Th17 cells maintain stable fungal commensalism in the oral mucosa
نویسندگان
چکیده
منابع مشابه
Tissue-Resident Macrophages in Fungal Infections
Invasive fungal infections result in high morbidity and mortality. Host organs targeted by fungal pathogens vary depending on the route of infection and fungal species encountered. Cryptococcus neoformans infects the respiratory tract and disseminates throughout the central nervous system. Candida albicans infects mucosal tissues and the skin, and systemic Candida infection in rodents has a tro...
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Figure Legend: Figure 1 Oral mucosa, Gingiva Ectopic tissue, Sebaceous gland in male F344/N rat from a chronic study. There are clusters of sebaceous glands in the gingiva. Figure 2 Oral mucosa, Gingiva Ectopic tissue, Sebaceous gland in male F344/N rat from a chronic study (higher magnification of Figure 1). The clusters of sebaceous glands in the gingiva are adjacent to a dilated duct. Figure...
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Microbial infection primes a CD8(+) cytotoxic T cell response that gives rise to a long-lived population of circulating memory cells able to provide protection against systemic reinfection. Despite this, effective CD8(+) T cell surveillance of barrier tissues such as skin and mucosa typically wanes with time, resulting in limited T cell-mediated protection in these peripheral tissues. However, ...
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ژورنال
عنوان ژورنال: Mucosal Immunology
سال: 2020
ISSN: 1933-0219,1935-3456
DOI: 10.1038/s41385-020-0327-1